TITLE : Nanoengineered Drug Combinations for Breast Cancer Treatment
نویسنده
چکیده
منابع مشابه
Nanoparticle delivery to metastatic breast cancer cells by nanoengineered mesenchymal stem cells
We created a 3D cell co-culture model by combining nanoengineered mesenchymal stem cells (MSCs) with the metastatic breast cancer cell line MDA-MD-231 and primary breast cancer cell line MCF7 to explore the transfer of quantum dots (QDs) to cancer cells. First, the optimal conditions for high-content QD loading in MSCs were established. Then, QD uptake in breast cancer cells was assessed after ...
متن کاملAnti-cancer and anti-immunomodulatory properties of novel Arteether in Folic acid-Chitosan-Fe3O4 composite nanoparticle for treatment of breast cancer
Goal: The potent anti-cancer activity of Arteether (ARE) has been the focus of many studies. However, the hydrophobic property of this drug limits its application. To increase the bioavailability of ARE, we formulated a nanosystem (NS) of folic acid (FA), chitosan (CS) and Fe3O4 for delivery of ARE against breast cancer. Material and Methods: The CS coated Fe3O4 was synthesized by co-precipitat...
متن کاملQuantification of Pathway Cross-talk Reveals Novel Synergistic Drug Combinations for Breast Cancer.
Combinatorial therapeutic approaches are an imperative to improve cancer treatment, because it is critical to impede compensatory signaling mechanisms that can engender drug resistance to individual targeted drugs. Currently approved drug combinations result largely from empirical clinical experience and cover only a small fraction of a vast therapeutic space. Here we present a computational ne...
متن کاملPreparation and Evaluation of a Liposome Drug Delivery System in Cancer Treatment in vitro
Cancer is a fatal disease and relatively widespread in the world; Breast cancer is the most prevalent cancer among women. Hydroxyurea (HU) is a chemotherapy drug for the cure of cancer different types in patients, for example breast cancer, but has several defects, for to remove these problems in this study a nanoliposome (NL) suspension for Hydroxyurea (HU) delivery in breast cancer cell thera...
متن کاملXWH - 09 - 1 - 0564 TITLE : Strategy for Restoring Drug Sensitivity to Triple - Negative Breast Cancer
s: Weiping Yu, Richa Tiwary, Bob G. Sanders and Kimberly Kline (2010) Targeting p73 as a strategy for enhancing anticancer efficiency of chemotherapeutic drugs to triple negative human breast cancers. 2010 AACR annual meeting, Washington, DC Weiping Yu, Richa Tiwary, Bob G. Sanders and Kimberly Kline (2011) -TEA cooperates with chemotherapeutic agents to induce apoptosis of p53-mutant, triple-n...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012